Gastric Cancer: Top 2025 Guide to Symptoms, Treatments & FAQs

March 25, 2025   399

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What Is Gastric Cancer?

Gastric cancer, commonly known as stomach cancer, is a disease in which malignant (cancer) cells form in the lining of the stomach. This cancer typically develops slowly over many years and often goes unnoticed in its early stages.

There are different types of gastric cancer, but the most common is adenocarcinoma, which starts in the mucus-producing cells of the stomach lining. Other types include gastrointestinal stromal tumors (GISTs), lymphomas, and carcinoid tumors, though these are much rarer.

Gastric vs Stomach Cancer: Is There a Difference?

While the terms "gastric cancer" and "stomach cancer" are often used interchangeably, "gastric" refers more specifically to the stomach itself, derived from the Latin word gaster. In medical literature and diagnostics, gastric cancer is the preferred term, while the general public may refer to it as stomach cancer. Despite the difference in terminology, both refer to the same condition — cancer that starts in the stomach.

Gastric Cancer Symptoms to Watch Out For

Early detection of gastric cancer can be life-saving. However, many symptoms are vague and commonly misattributed to less serious conditions like gastritis or indigestion.

Early vs Late-Stage Symptoms

• Early Stage: Bloating after meals, mild stomach discomfort, nausea, feeling full quickly
• Advanced Stage: Unexplained weight loss, blood in stool or vomit, persistent abdominal pain, trouble swallowing

Common Misinterpreted Symptoms

People may ignore persistent indigestion, heartburn not relieved by medication, and early satiety. If these symptoms persist, especially in those over 50 or with family history, consult a doctor immediately.

Diagnosing Gastric Cancer: Tools & Tests

Timely diagnosis is critical. Here’s how doctors detect gastric cancer:

• Upper Endoscopy (Gastroscopy)
• Biopsy
• CT Scans & MRI
• Blood Tests
• Barium Swallow Test

Current Gastric Cancer Treatments (2025)

Treatment depends on the stage and type of cancer, as well as the patient’s overall health. The major treatment options include:

• Surgery (Partial or Total Gastrectomy)
• Chemotherapy
• Radiation Therapy
• Immunotherapy
• Targeted Therapy

What Is Vyloy and How It Works?

In 2024, the FDA approved Vyloy (zolbetuximab), a targeted therapy for HER2-negative, CLDN18.2-positive gastric cancers. Used with standard chemotherapy, it showed improved survival rates in trials.

Role of Intraperitoneal Paclitaxel

The DRAGON-01 study in 2025 revealed promising results for combining intraperitoneal paclitaxel with systemic chemotherapy for patients with peritoneal metastasis.

Who Is at Risk of Stomach Cancer?

• People over 50
• Men more than women
• Family history of stomach cancer
• H. pylori infection
• Smokers
• High-salt or processed diet

How to Prevent Gastric Cancer Naturally

• Eat a diet rich in fruits, vegetables, and whole grains
• Reduce salt and processed meats
• Quit smoking
• Limit alcohol
• Treat H. pylori infections
• Exercise regularly

Prognosis and Survival Rates in 2025

Stage	5-Year Survival Rate
Stage I	~70%
Stage II	~45%
Stage III	~20%
Stage IV	<10%

Living With Gastric Cancer

After diagnosis, life changes. Patients benefit from:

• Nutritional guidance
• Support groups
• Rehabilitation programs
• Regular monitoring

Most Asked Questions About Gastric Cancer

What is gastric cancer?

Gastric cancer is a type of cancer that begins in the lining of the stomach.

What are the symptoms of gastric cancer?

Early symptoms include indigestion, bloating, and feeling full quickly. Advanced signs include weight loss and blood in stool.

Can gastric cancer be cured?

If detected early, gastric cancer is often curable through surgery and treatment.

What are the treatment options?

Treatment options include surgery, chemotherapy, radiation, targeted drugs, and immunotherapy.

Is stomach cancer the same as gastric cancer?

Yes, both terms refer to cancer that begins in the stomach.

How early can gastric cancer be detected?

With regular screenings and attention to symptoms, it can be caught in early, more treatable stages.

Conclusion: Awareness Is the First Step

Gastric cancer may be a silent threat, but awareness makes all the difference. Knowing the signs, understanding your risk, and seeking early screening could save your life or someone you love. Stay informed — and take control of your health today.